| ncRNA name | hsa-miR-155 |
| ncRNA Category | miRNA |
| Disease name | age-related macular degeneration (AMD) |
| Species | Homo sapiens |
| Tissues/Cell_line | human neocortical and retinal samples |
| Methods | miRNA sequencing, miRNA array |
| Expression pattern | up-regulated |
| Functional description | We report the sequence and abundance of a septet of sncRNAs that are significantly increased in abundance and common to both AD-affected superior temporal lobe neocortex and the AMD-affected macular region of the retina. Their target mRNAs are involved in the synchronization of amyloid production and clearance, phagocytosis, innate-immune, pro-inflammatory, and neurotrophic signaling and/or synaptogenesis. |
| PubMed ID | 29302837 |
| Year | 2018 |
| Title | Up-regulated Pro-inflammatory MicroRNAs (miRNAs) in Alzheimer's disease (AD) and Age-Related Macular Degeneration (AMD). |
| Drug-related ncRNA | NO |
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